https://www.ncbi.nlm.nih.gov/pubmed/28054261
OBJECTIVE: The low-level laser therapy (LLLT) has been reported as a therapeutic option for the painful TMD treatment. The aim of this study was to analyze the effect of LLLT on pain intensity (visual analogue scale, VAS), pain sensitivity in orofacial and corporal points (pressure pain threshold, PPT), and on Short Form-McGill Pain Questionnaire (SF-MPQ) indexes of women with myofascial pain (subtype of muscle TMD).
CONCLUSION: In conclusion, the LLLT active or placebo are effective in reducing the overall subjective perception of myofascial pain (VAS and SF-MPQ indexes); however, they have no effectiveness in reducing the pain sensitivity in orofacial and corporal points (PPT increase).
https://www.ncbi.nlm.nih.gov/pubmed/24801056
OBJECTIVE: Several clinical treatments have been proposed to manage symptoms of fibromyalgia. Low-level laser therapy (LLLT) may be a useful tool to treat this dysfunction.
CONCLUSION: After Laser Therapy or sham treatment, the number of tender points was significantly reduced in both groups (LLLT, p < 0.0001; placebo, p = 0.0001). However, all other fibromyalgia symptoms showed significant improvements after Laser Therapy compared to placebo (FIQ, p = 0.0003; McGill, p = 0.0078; and VAS, p = 0.0020). LLLT provided relief from fibromyalgia symptoms in patients and should be further investigated as a therapeutic tool for management in fibromyalgia. (NOTE: results are likely to drastically improve with appropriately higher power levels).
https://www.ncbi.nlm.nih.gov/pubmed/29080932
OBJECTIVE: Fibromyalgia is a chronic musculoskeletal condition characterized by widespread pain in the body and is associated with tender points at the shoulder, back and hip regions. A wide variety of pharmacologic drugs and dietary supplements have been used with limited success in treating the musculoskeletal pain. Early clinical studies with low level laser therapy (LLLT) alone or in combination with drugs commonly used to treat fibromyalgia suggested that LLLT may be effective in reducing musculoskeletal pain and stiffness, as well as the number of tender locations. However, a sham-controlled study reported that LLLT was not significantly better than the sham treatment and kinesiotape.
CONCLUSION: Although the 1Watt treatment produced minimal symptom relief, both the 42Watt and the 75Watt treatments produced a dramatic reduction in her overall pain, improved quality of sleep, and increased her level of physical activity for 4-10 days after these treatment sessions. This case illustrates the potential beneficial effects of using higher power levels of HILT for patients with fibromyalgia syndrome who have failed to respond to conventional interdisciplinary treatment regimens.
https://www.liebertpub.com/doi/abs/10.1089/acm.2011.0398
OBJECTIVE: This study evaluated the effects of Class IV laser therapy on pain, Fibromyalgia (FM) impact, and physical function in women diagnosed with FM
CONCLUSION: This study provides evidence that LHT may be a beneficial modality for women with FM in order to improve pain and upper body range of motion, ultimately reducing the impact of FM.
OBJECTIVE: In the April 2015 issue of Neuropsychiatric Disease and Treatment, our study found patients with Traumatic Brain Injury (TBI) responded extremely well to transcranial near-infrared laser treatment (NILT). Simply put, our team applied NILT directly to the location of the injury, allowing the laser to penetrate the skull and energize the damaged brain cells.
CONCLUSION: To date, little progress has been made in developing effective treatments for chronic mild- to moderate TBI or repetitive concussions. It’s become more pressing with rise in incidence among military veterans, and the epidemic-like sport-related concussions occurring virtually every minute and capturing the headlines. Here’s the good news: Patients in the study, and others since, report dramatic clinical improvement in their symptoms which are typically anxiety, depression, headaches, sleep disturbances, cognitive breakdowns, mood dysregulation and irritability.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468204/
OBJECTIVE: This study examined the effects of High Intensity Laser Therapy on pain and function of patients with chronic back pain.
CONCLUSION: High Intensity Laser Therapy can be an effective nonsurgical intervention method for reducing pain and helping the performance of daily routines of patients who have chronic back pain.
http://bmjopen.bmj.com/content/bmjopen/7/10/e017202.full.pdf
OBJECTIVE: This study examined the effects of High Intensity Laser Therapy on pain and function of patients with chronic back pain.
CONCLUSION: High Intensity Laser Therapy can be an effective nonsurgical intervention method for reducing pain and helping the performance of daily routines of patients who have chronic back pain.
http://bmjopen.bmj.com/content/bmjopen/7/10/e017202.full.pdf
OBJECTIVE: This study aims to evaluate the effect of high intensity laser therapy (HILT) in patients with lumbar disc protrusion (LDP).
CONCLUSION: After two weeks of treatment of two patient groups, ODI, VAS, lumbar flexion range and angle of straight leg raising significantly improved compared with their conditions before treatment (P< 0.01). A significant difference was noted in ODI, lumbar flexion range, and angle of straight leg raising between groups after two weeks of treatment (P< 0.05). Non-statistical significant difference was observed in lumbosacral portion pain and lower limb radiation pain with VAS (P> 0.05). However, difference in was VAS smaller in Group 1. All groups showed significantly different results in terms of ODI, lumbosacral portion pain, and lower limb radiation pain with VAS.
https://www.ncbi.nlm.nih.gov/pubmed/25141218
OBJECTIVE: The present study aimed to evaluate the pain reduction efficacy of treatment with the Ga-Al-As diode laser (980 nm) in combination with exercise therapy, in patients with chronic low back pain (CLBP).
CONCLUSION: This study demonstrated that the use of diode laser (980 nm) with large diameter spot size, in association with exercise therapy, appears to be effective. Such treatment might be considered a valid therapeutic option within rehabilitation programs for nonspecific CLBP.
https://www.ncbi.nlm.nih.gov/pubmed/27472858
OBJECTIVE: The present study aimed to evaluate the pain reduction efficacy of treatment with the Ga-Al-As diode laser (980 nm) in combination with exercise therapy, in patients with chronic low back pain (CLBP).
CONCLUSION: This study demonstrated that the use of diode laser (980 nm) with large diameter spot size, in association with exercise therapy, appears to be effective. Such treatment might be considered a valid therapeutic option within rehabilitation programs for nonspecific CLBP.
https://www.ncbi.nlm.nih.gov/pubmed/20414695
OBJECTIVE: The purpose of this study was to compare the effectiveness of low-level laser therapy (LLLT) on pain and functional capacity in patients with acute and chronic low back pain caused by lumbar disk herniation (LDH).
CONCLUSION: There were no differences between laser and placebo laser treatments on pain severity and functional capacity in patients with acute and chronic low back pain caused by LDH.
LLLT - Low Level Laser Therapy does not work for back pain!
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412059/pdf/pho.2012.3240.pdf
OBJECTIVE: Laser therapy has been proposed as a physical therapy for musculoskeletal disorders and has attained popularity because no side effects have been reported after treatment. However, its true effectiveness is still controversial because several clinical trials have reported the ineffectiveness of low level lasers in treating pain.
CONCLUSION: The review shows that laser therapy on the joint reduces pain in patients. Moreover, when we restrict the energy doses of the laser therapy into the dose window suggested in the previous study, we can expect more reliable pain relief treatments.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418129/
OBJECTIVE: To determine a therapeutic dose range for laser therapy for increasing blood flow to the forearm.
CONCLUSION: Compared with baseline, blood flow increased over time with the 3-W treatment (F3,9 = 3.468, P < .011) at minute 4 of treatment (2.417 ± 0.342 versus 2.794 ± 0.351 mL/min per 100 mL tissue, P = .032), and at 1 minute (2.767 ± 0.358 mL/min per 100 mL tissue, P < .01) and 2 minutes (2.657 ± 0.369 mL/min per 100 mL tissue, P = .022) after treatment. The sham, 1-W, and 6-W treatment doses did not change blood flow from baseline at any time point. Laser therapy at the 3-W (360-J) dose level was an effective treatment modality to increase blood flow in the soft tissues.
https://www.ncbi.nlm.nih.gov/pubmed/26914684
OBJECTIVE: The aim of the study was to investigate the effect of high-intensity laser therapy (HILT) in treatment of patients with chronic neck pain (CNP) on cervical range of motion (ROM), pain, and functional activity.
CONCLUSION: Statistical analyses were performed to compare the differences between baseline and post-treatment. The level of statistical significance was set as p < 0.05. Cervical ROM significantly increased after 6 weeks of treatment in all groups. VAS and NDI results showed significant decrease post-treatment in both groups. HILT + EX effectively increased cervical ROM and decreased VAS and NDI scores after 6 weeks of treatment compared to PL + EX. HILT + EX is an effective physical therapy modality for patients with CNP compared to PL + EX therapy. The combination of HILT + EX effectively increased cervical ROM, functional activity, and reduced pain after 6 weeks of treatment.
https://www.ncbi.nlm.nih.gov/pubmed/28626329
OBJECTIVE: This study examined the effects of High Intensity Laser Therapy on pain and function of patients with chronic back pain.
CONCLUSION: High Intensity Laser Therapy can be an effective nonsurgical intervention method for reducing pain and helping the performance of daily routines of patients who have chronic back pain.
https://www.ncbi.nlm.nih.gov/pubmed/25274197
OBJECTIVE: Myofascial pain syndrome (MPS) of the trapezius muscle is one of the main causes of neck pain. In this randomized, double-blind study, we evaluated the effects of high-intensity laser therapy (HILT) in female patients with chronic MPS of the trapezius muscle.
CONCLUSION: In a comparison of the percentage changes in the parameters at weeks 4 and 12 relative to pretreatment values, the HILT group showed greater improvement in pain scores, the neck disability index, and several subparts of the short-form 36 health survey (SF-36) (physical functioning, role limitations due to physical functioning, bodily pain, general health perceptions, social functioning, and role limitations due to emotional problems) than did the sham therapy group. We conclude that HILT is an effective therapeutic method in the treatment of patients with chronic MPS of the trapezius muscle.
https://clinicaltrials.gov/ct2/show/NCT01992627
OBJECTIVE: The diagnosed patients with epicondylosis will be treated with laser therapy for a total of four sessions during the entire duration of the treatment protocol. Parameters to be evaluated are tenderness, pain upon active resistive motion and DASH scores. After every treatment session of laser therapy, these said parameters will be recorded initially on the first treatment, one week after the initial treatment, two weeks after the initial treatment and four weeks after the initial treatment.
CONCLUSION: Pending...
https://www.high-intensity-laser.com/study-4
OBJECTIVE: High Intensity Laser and Radial Shockwave Therapy are two non – invasive approaches used previously in the treatment of musculoskeletal pain. We hypothesize that the use of these techniques may reduce recovery time, improve pain control and reduce medication in second - degree ankle sprains.
CONCLUSION: The use of High Intensity Laser therapy could be used as part of the treatment protocol for second - degree ankle sprains, as it reduces significantly pain and the use of medication. Radial Shockwave Therapy also showed some effects, but has more evidence in chronic tendinopathies. The role of HIL in acute injuries or tendinopathies and RSWT in chronic tendinopathies, seem to be positive and should be prescribed independently as part of the treatment protocols, being non-invasive and with no reported complications.
https://www.ncbi.nlm.nih.gov/pubmed/12804422
OBJECTIVE:
CONCLUSION: Despite some positive findings, this meta-analysis lacked data on how LASER THERAPY effectiveness is affected by four crucial factors: wavelength, treatment duration of LASER THERAPY, dosage and site of application over nerves instead of joints. There is clearly a need to investigate the effects of these factors on LASER THERAPY effectiveness for OA in randomized controlled clinical trials.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442599/
OBJECTIVE: Recent reviews have indicated that low level level laser therapy (LLLT) is ineffective in lateral elbow tendinopathy (LET) without assessing validity of treatment procedures and doses or the influence of prior steroid injections.
CONCLUSION: LLLT administered with optimal doses of 904 nm and possibly 632 nm wavelengths directly to the lateral elbow tendon insertions, seem to offer short-term pain relief and less disability in LET, both alone and in conjunction with an exercise regimen. This finding contradicts the conclusions of previous reviews which failed to assess treatment procedures, wavelengths and optimal doses.
https://www.ncbi.nlm.nih.gov/pubmed/19877824
OBJECTIVE: There are conflicting reports regarding the efficacy of low energy laser therapy in treatment of lateral epicondylitis (LE). Contradictory results are considered to be due to different joint treatment protocols regarding variables such as dose, duration, and frequency. The aim of this study was to investigate the efficacy of gallium-arsenide (GaAs) laser therapy, which was performed with the dose regimen recommended by the World Association for Laser Therapy, in relieving pain and improving functional activities in patients with LE.
CONCLUSION: Although low energy laser therapy had no advantage compared to placebo in patients with LE for the short term, a significant improvement, particularly in functional parameters, was achieved in the long term. Laser, which has relatively no side effects, might be included among long-term treatment options for LE.
(NOTE: W.A.L.T. is out of touch with reality - LLLT does not work, more appropriate higher doses are necessary for better outcomes.)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412059/pdf/pho.2012.3240.pdf
OBJECTIVE: Laser therapy has been proposed as a physical therapy for musculoskeletal disorders and has attained popularity because no side effects have been reported after treatment. However, its true effectiveness is still controversial because several clinical trials have reported the ineffectiveness of lasers in treating pain.
CONCLUSION: Obtaining pain relief from LLLT might be a good alternative to the use of NSAIDs, particularly for elderly people, because laser therapy has no reported side effects.47 In addition, clinical studies have reported that applying laser therapy in addition to exercise might show greater pain reduction effects than using laser therapy alone.2,22 In conclusion, investigations pertaining to laser therapies have indicated that laser irradiation on joint areas can be an effective pain relief treatment when appropriate energy doses are selected.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729198/
OBJECTIVE: The purpose of this scoping review was to identify and synthesize literature on dosage variables on the efficacy of low-level laser therapy (LLLT) for neuromusculoskeletal conditions.
CONCLUSION: Although many articles were found on LLLT for neuromusculoskeletal conditions, the studies had amorphous parameters. A heterogeneity of reported doses precluded the synthesis of sufficient evidence to correlate dosage variables with improved or unimproved outcomes. Therefore, based on the current literature, dosage variables for the efficacy of LLLT for neuromusculoskeletal conditions are uncertain at this time. (NOTE: Higher power is necessary for better treatment outcomes).
OBJECTIVE: Sports Medicine Specialization School at the University of Bologna Research activities in the therapeutic and rehabilitative sector have always pursued the goal of maximum effectiveness and minimum invasiveness in the surgical, pharmacological and instrumental fi elds. This has led to the developing of a wide variety of electromedical devices, especially in the physical therapy sector, but over the years these have unfortunately resulted in being of no or very little use.
CONCLUSION: This facility, like so many others, has not tested the efficacy of higher dose photomedicine (laser therapy). Why? W.A.L.T., N.A.A.L.T., Thor Lasers, MultiRadiance, Erchonia Lasers, Chattanooga, Terraquant, and so many more Low Level adherents PREVENT information on higher-dose lasers from reaching the public, thereby depriving patients of healing and pain relief from appropriately higher dosages to make more money.
https://www.ncbi.nlm.nih.gov/pubmed/28772237
OBJECTIVE: Acute arthritis is an inflammation that affects many joints. The principal treatment options comprise drugs (corticosteroids), invasive and painful surgery. The objective of this study was to evaluate the efficacy of low intensity laser therapy (LILT), a non-invasive treatment, in a murine model of acute inflammation model. 48 mice received a synovial injection of Zymosan A into one knee.
CONCLUSION: LILT showed signs of an anti-inflammatory effect when applied once, but promoted increased resorptive area when used for two sessions, indicating the importance of a controlled LILT protocol to reach therapeutic effects.
https://www.ncbi.nlm.nih.gov/pubmed/28688752
OBJECTIVE: The aim of this paper is to study the in vivo potency of low-level laser therapy (LLLT) and low intensity pulsed ultrasound (LIPUS) alone, accompanied by bone grafts, or accompanied by other factors on fracture healing in animal models and patients.
CONCLUSION: If it is confirmed that the therapeutic influence is true and reliable, patients will obtain benefits from LIPUS and LLLT. Further clinical trials of high methodological quality are needed in order to determine the optimal role of LIPUS and LLLT in fracture healing in patients. (NOTE: Higher dosages are needed for treatment efficacy).
https://www.ncbi.nlm.nih.gov/pubmed/12215864
OBJECTIVE: The purpose of this study was to examine the effectiveness of low power laser (LPL) and low-dose amitriptyline therapy and to investigate effects of these therapy modalities on clinical symptoms and quality of life (QOL) in patients with fibromyalgia (FM)
CONCLUSION: A significant difference was observed in depression score (P = 0.000) in the amitriptyline group in comparison to the laser group after therapy. Our study suggests that both amitriptyline and laser therapies are effective on clinical symptoms and QOL in fibromyalgia and that Ga-As laser therapy is a safe and effective treatment in cases with FM. Additionally, the present study suggests that the Ga-As laser therapy can be used as a monotherapy or as a supplementary treatment to other therapeutic procedures in FM.
OBJECTIVE: Traumatic brain injury (TBI) is a growing health concern effecting civilians and military personnel. Research has yielded a better understanding of the pathophysiology of TBI, but effective treatments have not been forthcoming. Near-infrared light (NIR) has shown promise in animal models of both TBI and stroke. Yet, it remains unclear if sufficient photonic energy can be delivered to the human brain to yield a beneficial effect.
CONCLUSION: Our recent tissue studies demonstrate no penetration of low level NIR energy through 2 mm of skin or 3 cm of skull and brain. However, at 10–15 W, 0.45%–2.90% of 810 nm light penetrated 3 cm of tissue. A 15 W 810 nm device (continuous or non-pulsed) NIR delivered 2.9% of the surface power density. Pulsing at 10 Hz reduced the dose of light delivered to the surface by 50%, but 2.4% of the surface energy reached the depth of 3 cm. Approximately 1.22% of the energy of 980 nm light at 10–15 W penetrated to 3 cm. These data are reviewed in the context of the literature on low-power NIR penetration, wherein less than half of 1% of the surface energy could reach a depth of 1 cm. NIR in the power range of 10–15 W at 810 and 980 nm can provide fluence within the range shown to be biologically beneficial at 3 cm depth.
https://www.bostonmagazine.com/health/2017/11/27/li-huei-tsai-alzheimers-treatment/
OBJECTIVE: Within months, they began testing the effect of LED light on the Alzheimer’s brain, effectively fusing Tsai’s early findings and the German researchers’ nearly forgotten breakthrough. Slowly, it appeared that repeated exposure to pulsating lights could vanquish amyloid plaques and tau tangles, two protein deposits that lead to cognitive decline in Alzheimer’s patients.
CONCLUSION: While Tsai’s work involves stimulating the visual cortex with lights flashing at a relatively high frequency, Tanzi’s uses lower-frequency light transmitted through LED goggles. His lab has also experimented with direct transcranial stimulation, which uses an electrical current instead of lights to arouse the brain. This technique, he says, could actually offer better results than LED therapy, which he posits might not spread far beyond the eyes. Light “hits the visual cortex, and it gets those nerve cells firing at that certain rate, and then you have to hope that the rest of the brain will follow suit,” Tanzi explains.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066074/pdf/main.pdf
OBJECTIVE: The brain suffers from many different disorders that can be classified into three broad groupings: traumatic events (stroke, traumatic brain injury, and global ischemia), degenerative diseases (dementia, Alzheimer's and Parkinson's), and psychiatric disorders (depression, anxiety, post traumatic stress disorder). There is some evidence that all these seemingly diverse conditions can be beneficially affected by applying light to the head.
CONCLUSION:
List of brain disorders that can be treated by dose specific Laser Therapy:
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